BIOL 2020: Principles of Cell Biology

Lectures and discussions will explore the relationship between cell structure and function and the experimental foundation underlying the science of cell biology, using examples from both prokaryotes and eukaryotes (plants, animals, and fungi).

Students successfully completing Principles of Cell Biology will understand:

Theories and evidence for important milestones in the evolution of cells;

The structure, function, and assembly of important cellular macromolecules, including proteins, lipids and membranes, mono-, di-, and polysaccharides, and nucleic acids;

• How cells harvest, store, and use chemical energy, and the enzymes and organelles used in these processes;

• The storage, flow, and regulation of genetic information in cells, in the contexts of cell function and inheritance;

• The processes of exocytosis, endocytosis, and phagocytosis in eukaryotes, and the signals and mechanisms for targeting proteins and vesicles to the correct intracellular targets;

• The structure and function of the cytoskeleton in eukaryotes and prokaryotes;

• The regulation and mechanisms of cell proliferation and cell division in eukaryotes and prokaryotes;

• The processes and mechanisms related to the organization and function of cells into multicellular communities and organisms, including: (1) cell communication and signal transduction mechanisms, and signaling cascades; (2) cell adhesion and cell junctions, and (3) cell and tissue renewal and stem cells.

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